Mitochondria-encoded peptide for AMPK and metabolic research.
MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA Type-C) is a 16-amino acid mitochondria-derived peptide encoded in the mitochondrial genome. Research has examined its role as a metabolic regulator that activates AMPK, enhances insulin sensitivity, and promotes mitochondrial biogenesis via PGC-1α upregulation. MOTS-c translocates to the nucleus under metabolic stress where it modulates gene expression related to glucose metabolism and oxidative stress response. Studies in cellular and animal models have linked MOTS-c to exercise mimicry and metabolic homeostasis. Supplied as lyophilized powder, ≥99% HPLC purity, LC-MS confirmed.
Quality Verification
≥99% Purity by HPLC
LC-MS Identity Confirmed
Endotoxin Tested (LAL)
Lyophilized Powder
Cold-Chain Shipped
Compound Specifications
CAS Number
1457306-06-7
Class
Mitochondrial-Derived Peptide
Molecular Weight
~2,174 Da
Sequence
16 Amino Acids
Form
Lyophilized Powder
Purity
≥99% by HPLC
Storage
−20°C lyophilized · 4°C reconstituted up to 7 days
Lone Star Peptide ships same-day to research institutions across all of Texas. Same-state logistics mean shorter cold-chain transit and faster delivery than any out-of-state supplier — with COA documentation that meets institutional procurement standards statewide.
FOR RESEARCH USE ONLY, MOTS-C is supplied exclusively for in vitro and laboratory research applications. Not approved by the FDA for human consumption or therapeutic use. Not a drug, supplement, or medical treatment. Purchasers are responsible for compliance with all applicable regulations.
Does MOTS-c ship to Texas?+
Yes. MOTS-c ships to all Texas locations with same-day dispatch from Houston for orders placed before 2 PM CST. Typical arrival is 1–2 business days to Dallas, Austin, San Antonio, Fort Worth, and all Houston metro areas.
What is the purity of your MOTS-c?+
Our MOTS-c is verified at ≥99% purity by HPLC. Every batch includes a COA with HPLC chromatogram, LC-MS identity confirmation, and endotoxin testing from Freedom Diagnostics. Batch records are publicly accessible in our COA library.
What does a MOTS-c COA include?+
Each COA includes: HPLC chromatogram (≥99% purity), LC-MS mass spectrometry for identity confirmation, endotoxin test results, batch number, and synthesis date. All records are publicly viewable in the batch COA library.
Is MOTS-c available for research in Houston?+
Yes. As a Houston-based supplier, we offer same-day shipping to Texas Medical Center researchers, UT Health Science Center, Baylor College of Medicine, Houston Methodist Research Institute, and MD Anderson Cancer Center. For in vitro laboratory research use only.
What sizes does MOTS-c come in?+
MOTS-c is available in 5mg and 10mg vials for research use.
What is the batch number for MOTS-c?+
Current batch records for MOTS-c are available in our public COA library. Each batch number corresponds to a specific Freedom Diagnostics test report with HPLC and LC-MS data.
